Diagnostics

Diagnostics (7)

Thứ năm, 11 Tháng 1 2024 18:03

Talent Screening

TALENT Screening

Early childhood development is key to raising healthy and successful children. As children learn and develop faster in the first few years of life, building a solid foundation for them during this period helps shape their lifelong health, educational achievement, economic success and happiness in life

Importance of Early Childhood Development

Help Your Child Achieve Success in Life Through DNA Testing.

Should I Get My Child Tested?

Every parent wants to raise happy and successful children. By getting your child tested, you will have information backed by science to help you develop and manage your child. Parenting is not easy, but you can use Cordlife TALENT to make it easier.*

What is Cordlife TALENT Screening?

Every child is unique.

Cordlife TALENT screening is a DNA testing service that uses cutting-edge technology to help you learn more about your child. Our insight reports will include information about your child in the key categories.

Benefits of Cordlife TALENT Screening

Helps you save time and money because you can direct resources to areas where your child is most likely to excel

Let you tailor enrichment programmes to suit your child’s learning style.

Let your child feel motivated because their innate talents can make learning easier.

Let you apply the right parenting style to fit your child’s personality.

Take The First Step Today To Shape Your Child’s Future!

Cordlife TALENT Package

Gain comprehensive insight into your child to help you better manage and develop your child today.

Talent & Traits

Screening Test Categories

Item

Talent Traits

  • Linguistic
  • Musical Talent
  • Reading Talent
  • Creativity
  • Learning Ability
  • Logical Thinking
  • Concentration
  • Mathematical Talent

Character Traits

  • Self reflection
  • Stress Resistance
  • Empathy
  • Depression Tendency
  • Interpersonal Intelligence
  • Affinity

Sport

  • Muscle Endurance
  • Muscle Explosiveness

Total Items

16

Why Cordlife TALENT Screening?

EASY AND NON-INVASIVE COLLECTION

Collection is really easy! You can easily collect your child’s DNA at the comfort of your home using an oral swab included in the collection kit. The collection kit will come with easy-to-follow instructions and materials required for the collection.

GET TESTED ONLY ONCE IN YOUR CHILD’S LIFETIME

As DNA base pairs do not change much over a person’s lifetime, you only need to let your child get tested once and the results generated will last a lifetime.

DESIGNED FOR ASIAN POPULATION

Cordlife TALENT is specially developed for the Asian population. Our partner laboratory uses genome-wide association studies, constituting a large Asian genome database, to provide you with the most accurate interpretation.

EASY TO UNDERSTAND INSIGHT REPORTS

Cordlife TALENT insight reports are comprehensive and easy to understand. The reports will include recommendations that are best for your child.

GET STARTED IN A FEW SIMPLE STEPS

Step 1: Order a kit

Begin your journey by ordering a kit for your child.

Step 2: Collect sample & ship

Collection of your child’s DNA is easy and painless. Simply collect the sample and mail it out. Read the instructions here before you start.

Step 3: Receive the test results

The test results will be sent to you within 6 to 8 weeks after the collection via a secured and encrypted email.

*This service is brought to you by Cordlife Technologies Pte.Ltd. The sample will be sent to Cordlife (Hong Kong) Limited in partnership with third-party laboratory. The information contained in the testing reports is not meant to substitute qualified medical advice and is for reference only. The results of this test do not provide a definitive genetic interpretation and should not be used to assess, diagnose, prevent or treat any medical conditions.

Talent 4

SGD 238

Linguistic

Self Reflection

Stress Resistance

Muscle Endurance

Talent 8

SGD 338

Musical Talent

Reading Talent

Creativity

Stress Resistance

Empathy

Depression Tendency

Muscle Endurance

Muscle Explosiveness

Talent 16

SGD 438

Linguistic

Musical Talent

Reading Talent

Creativity

Learning Ability

Logical Thinking

Concentration

Mathematical Talent

Self Reflection

Stress Resistance

Empathy

Depression Tendency

Interpersonal Intelligence

Affinity

Muscle Endurance

Muscle Explosiveness

Thứ tư, 10 Tháng 1 2024 16:50

Metascreen

YOUR BABY’S FIRST STEP TO A HEALTHY LIFE

Why Metabolic Screening?

Newborn with metabolic disease are most severe and can lead to death

Metabolism is a set of chemical reaction processes, in which enzymes play an important role in breaking down and converting food into energy to maintain the body’s operation, such as the immune system, physical development and brain development, etc.; it can also digest food Get energy to ensure proper functioning of the body.

Newborn infants with metabolic diseases (congenital metabolic deficiencies) due to the lack of some enzymes for normal metabolic function, the body accumulates too many toxic substances or lacks important nutrients. Although metabolic diseases are relatively rare, if proper treatment is not performed in time, metabolic diseases can lead to disability in the limbs, lifelong disabilities, and intellectual disability. In the most serious cases, it can lead to death.

An Affected Baby may Appear Normal

An Affected Baby may Appear Normal

Affected baby lacks enzyme to breakdown milk properly.

Affected baby becomes sick, with symptoms like vomiting, seizures, poor feeding, lethargy or developmental delays.

Meta 100+ is the most comprehensive non-invasive newborn metabolic screening test

Newborn metabolic screening can either be done with your newborn’s urine (Meta 100+) or blood specimen (Meta 56). The difference between using urine and blood for newborn screening is the number of metabolic disorders detectable. Screening your newborn will facilitate early treatment and prevent long term detrimental effects to your baby’s health.

Reliably detects more than 100 metabolic disorders

FDA-approved GC-MS technology combined with proprietary bioinformatics to reliably detect more than 100 metabolic disorders.

Simple and painless urine test

Your baby’s urine can be easily collected by inserting filter paper into the diaper without causing any harm or discomfort to your baby.

Suitable to babies up to 6 months*

Your baby’s urine can be easily collected by inserting filter paper into the diaper without causing any harm or discomfort to your baby.

Timely screening report

The results will be available within 10-14 working days to enable early treatment, if necessary.

International accreditation

The laboratory is located at Hong Kong Science and Technology Park which has stringent standards for laboratory operations, quality and technology.

Highly Accurate & Specific

Metascreen® uses a gas-chromatography mass spectrometry (GC-MS) technology manufactured by Shimadzu, Japan. After processing the urine specimen through GC-MS, we analyse the GC-MS data using proprietary planar bioinformatics first developed by Japanese researchers. The planar bioinformatics makes use of multiple analytes (metabolites) from more than one biochemical (metabolic) pathway to identify a single metabolic disorder. This means that the results would be more reliable and accurate than traditional technology using mass tandem spectrometry (MS-MS) because MS-MS only uses about 1 or 2 analyte profiles for each disorder, and often, the same analyte profile is used for multiple disorders.

CAP Accredited Laboratory

CAP (The College of American Pathologists) accreditation is the highest standard for management and processes of a laboratory, focusing on reliability, accuracy and quality. This accreditation is given to facilities after a rigorous site inspection accompanied by an examination of the records and quality of the facility's management system. Cordlife's commitment and focus on quality was recognized when our facility earned the prestigious CAP accreditation.

About 1 in every 1,250 babies1 is expected to be born with an inherited metabolic disorder.

Screening your newborn will facilitate early treatment and prevent long term detrimental effects to your baby’s health.

Groups of inborn errors of Metabolism (IEMs) Meta 56 Meta 106
Amino acidopathies and organic acidemia 30 59
Disorders of sugar metabolism - 8
Disorders of urea cycle 8 -
Disorders of fatty acid metabolism 12 16
Peroxisomal diseases - 5
Disorders of purine and pyrimidine metabolism - 9
Lactic acidemia and hyperpyruvic metabolism - 7
Other IEMs 6 12
56 106

Highly reliable testing platform

Using FDA-approved GC-MS technology, Metascreen ® is a non-invasive urine test that screens more than 100+ metabolic disorders without causing any harm or discomfort to your baby. As many metabolic disorders are organic acid disorders (also known as “organic acidemias”), they can be detected more accurately using urine, based on the abnormal excretion patterns of the metabolites as a result of faulty metabolism caused by the disorder. Because our kidneys can efficiently remove unwanted or toxic metabolites from the blood, such compounds are excreted in large amounts in the urine, but may not be found in significant concentrations in blood.2

The American College of Medical Genetics (ACMG) actually recommends urine organic analysis as the diagnosis step for many of metabolic disorder, should there be a positive newborn screening result using the dried blood spot analysed by tandem mass spectrometry (MS/MS).3,4

METASCREEN®GC-MS TECHNOLOGY OTHER TEST MS-MS TECHNOLOGY
Invasiveness Baby’s urine Baby’s bloods from heel prick
Number More than 100 disorders Around 20-30 disorders
Accuracy rate 99%4 Higher false positive (0.07- 3.00%)5
Specificity Specific result using multiple analyte profiles Confirmatory test is needed for verification
Time to diagnose From screening and confirmation to diagnosis From screening to confirmation then finally to diagnosis

More than 100+ metabolic conditions tested

  1. Propionic aciduria
  2. Holocarboxylase synthetase deficiency
  3. Methylmalonic aciduria (Cbl C and Cbl D)
  4. Methylmalonic Aciduria
  5. Methylmalonic aciduria (Cbl A and Cbl B)
  6. Malonic aciduria
  7. Isobutyryl-CoA dehydrogenase deficiency
  8. 2-methylbutyryl-CoA dehydrogenase deficiency
  9. Methylmalonic Semialdehyde Dehydrogenase Deficiency
  10. Beta-ketothiolase deficiency
  11. Isovaleric aciduria
  12. 3-Methylcrotonylglycinuria
  13. 3-Methylglutaconic aciduria (type I – hydratase deficiency)
  14. Barth Syndrome
  15. 3-hydroxy 3-methyl glutaric aciduria
  16. Glutaric aciduria type II(H-PHE)
  17. Glutaric aciduria type I
  18. Mevalonate kinase deficiency
  19. Glyceroluria
  20. Phenylketonuria (phenylalanine hydroxylase deficiency)
  21. Hyperphenylalaninuria (variant, benign)
  22. 2-Methyl 3-hydroxy butyric aciduria
  23. Tyrosinuria type I (hepatorenal tyrosinemia)
  24. Tyrosinuria type II (oculocutaneous tyrosinemia)
  25. Tyrosinuria type III (4-hydroxyphenylpyruvate dioxygenase def.)
  26. Transient Tyrosinuria of the newborn
  27. Tyrosinuria caused by a liver disease
  28. Maple syrup urine disease
  29. N-acetylglutamate synthase deficiency
  30. Carbamylphosphate synthetase deficiency
  31. Ornithine transcarbamylase deficiency
  32. Citrullinuria (argninosuccinate synthase deficiency)
  33. Citrullinuria type II (citrin deficiency)
  34. Argininosuccinic aciduria
  35. Argininuria
  36. Hypermethioninuria (MAT I/III deficiency)
  37. Homocystinuria cystathionine beta-synthase deficiency
  38. Alkaptonuria
  39. Tada syndrome
  40. Encephalopathy due to hydroxykynureninuria
  41. Valinuria
  42. Hyperleucine-isoleucinuria
  43. Dihydrolipoyl dehydrogenase(E3) deficiency
  44. Beta-hydroxyisobutyryl CoA deacylase deficiency
  45. Histidinuria
  46. Hartnup syndrome
  47. Lysinuric protein intolerance
  48. Alpha-ketoadipic aciduria
  49. Saccharopinuria
  50. Seizures-intellectual deficit due to hydroxylysinuria
  51. Cystathioninuria
  52. Hyperprolinuria type I
  53. Hyperprolinuria type II
  54. Hyper hyperprolinuria
  55. Hawkinsinuria
  56. Biotinidase deficiency
  57. Fumarate hydratase deficiency
  58. Hyperornithinuria-Hyperammonuria-Homocitrullinuria Syndrome
  59. 2-hydroxyglutaric aciduria
  1. Classic galactosenuria
  2. Galactokinase deficiency
  3. Galactose epimerase deficiency
  4. Transient galactonuria
  5. D-glyceric aciduria
  6. Fructose-1, 6-Diphosphatase Deficiency
  7. Endogenous sucrosuria
  8. Lactose intolerance
  1. Short-chain acyl-CoA dehydrogenase deficiency
  2. Medium-chain acyl-CoA dehydrogenase deficiency
  3. Medium/short-chain L-3-OH acyl-CoA DH deficiency
  4. Long-chain 3-OH acyl-CoA dehydrogenase deficiency
  5. Ethylmalonic encephalopathy
  6. Dicarboxylic aciduria
  1. Zellweger syndrome
  2. Neonatal adrenoleukodystrophy
  3. Infantile Refsum disease
  4. Zellweger-like syndrome
  5. Primary Hyperoxaluria
  1. Disorders of Purine, Pyrimidine Metabolism
  2. Lesch-Nyhan syndrome
  3. Kelley-Seegmiller syndrome
  4. Adenine phosphoribosyltransferase deficiency
  5. Hereditary xanthinuria
  6. Orotic aciduria
  7. Dihydropyrimidine dehydrogenase deficiency
  8. Dihydropyrimidinase deficiency
  9. Beta-ureidopropionase deficiency
  1. Pyruvate dehydrogenase e1-beta deficiency
  2. Pyruvate dehydrogenase phosphatase deficiency
  3. Pyruvate carboxylase deficiency
  4. Pyruvate decarboxylase deficiency
  5. Leigh syndrome
  6. Cytochrome c oxidase deficiency
  7. De Toni-Debré-Fanconi syndrome
  1. Hyperglycinuria
  2. Sarcosinuria
  3. Imidazole aminoaciduria
  4. Formiminoglutamic aciduria
  5. Carnosinuria
  6. Canavan disease
  7. Glutathione synthetase deficiency
  8. Gamma-glutamyl transpeptidase deficiency
  9. Succinic semialdehyde dehydrogenase deficiency
  10. Hyperpipecolaturia
  11. Neonatal intrahepatic cholestasis caused by citrin deficiency
  12. Beta-aminoisobutyric aciduria

Metascreen® Enrolment Process

Your baby’s first step to a healthy life. Enrolling Metascreen® for your baby now.

Enrolment

Call us for service enrolment and get collection kit.

Sample Collection

Collect your baby’s urine sample when baby is at least 2 days old and has taken at least one feed 24 hours ago.

Sample Pick-up

Call our hotline and courier service will be arranged for sample pick up.

Testing & Analysis

Your baby’s urine sample will be screened and analysed for metabolic disorders using GC-MS technology.

Reporting & Follow Up

We will arrange a follow up consultation if the test result is positive.

Real Stories

Tyrosinemia Type I

Tyrosinemia Type I is a type of amino acid disorder characterised by the lack of fumarylacetoacetate hydrolase (FAH), an enzyme required to breakdown the amino acid tyrosine; If left untreated, the condition can potentially result in a wide variety of symptoms including liver & kidney failures, developmental delays, increased risk of liver cancer, etc.

Phenylketonuria (PKU)

Phenylketonuria (also known as PKU) is a congenital disorder that increases the levels of phenylalanine in the blood. Phenylalanine is the building block of proteins that are obtained through dietary intake of food such as meat, fish, beans, eggs and some artificial sweeteners.If left untreated, phenylalanine can build up to harmful levels in the body, causing permanent intellectual disability and other serious health problems; Affected infants usually become apparent by 6 months of age with signs of mental retardation.

Primary Hyperoxaluria

Matthew was born in February 2011 with a rare genetic disorder called Primary Hyperoxaluria Type 1. This was difficult for the family as Matthew’s sister has the same condition, though she had not experienced serious symptoms. However, Matthew were suffering serious symptoms which affected his liver as well as his kidney and he has been on dialysis at least 6 days a week since he was 5 months old. However, all the medications and dialysis did not improve Matthew’s liver and kidneys. Finally, he got liver and kidney transplant on 2013.

Canavan Disease

Canavan disease is a progressive and fatal cerebral degenerative disease that begins in infancy. This inherited genetic abnormality is caused by mutations in the gene for an enzyme which causes deterioration of the white matter (myelin) in the brain Symptoms such as mental retardation, lack of head control etc, usually become noticeable at the age of three to nine months old. Many children do not live past age 10.Although there is currently no cure for Canavan disease, the present treatment involves managing the symptoms.

Disclaimer

Metascreen is a trademark or registered trademark of Cordlife Group Limited, a Singapore Exchange Mainboard listed company. The screening test offered under the brand is conducted by Cordlife (Hong Kong) Ltd., a CAP-accredited laboratory committed to providing early and accurate detection of metabolic disorders in newborn babies. Cordlife (Hong Kong) Ltd. has a quality management system in place to ensure maximum accuracy of screening results. As with any laboratory tests, false positive or false negative results cannot be completely eliminated due to various reasons including but not limited to age of patient at the time of specimen collection, patient’s health status, specimen quality and other variables. Hence, the risk of a disorder should never be precluded solely on the basis of screening. Signs or symptoms observed should be followed up immediately by a professional healthcare provider.

Sources

1) Guerrero RB, Kloke KM, Salazar D. Inborn Errors of Metabolism and the Gastrointestinal Tract. Gastroenterol Clin North Am. 2019 Jun;48(2):183-198. 2) Bouatra S, Aziat F, Mandal R, Guo AC, Wilson MR, et al. The Human Urine Metabolome. PLoS ONE. .2013, 8(9): e73076.
3) Michael J. Laboratory Medicine Practice Guidelines. Follow-up Testing for Metabolic Diseases Identified by Expanded Newborn Screening Using Tandem Mass Spectrometry. The National Academy of Clinical Biochemistry. 2009
4) Berdasarkan data internal, Juni 2020.
5) D. Matern, K. Raymond, S. Tortorelli, et al. Improving NBS Performance: The Mayo Clinic Experience Report.

Thứ tư, 10 Tháng 1 2024 12:14

Cordlife Baby Genetic Screening

Baby Genetic Screening

Cordlife Baby Genetic Screening

Screens 0-3 years babies with more than 241 conditions caused by chromosomal abnormalities and disease-causing gene variants, providing you an expanded insight of your baby’s health condition.

Quick and Effective

Only a simple heel prick is required for testing.

Clinically validated technology

It uses high-density single nucleotide polymorphism (SNP) microarray platform for testing, which is the recommended first-tier genetic investigation for many conditions, including autism and intellectual disability.

Internationally certified laboratory

The sample will be tested by our CLIA-certified clinical lab partner based in South Korea. Managed by USFDA, CLIA sets stringent quality standards for labs performing tests on human specimens to ensure accurate, reliable and timely results. Currently, only CLIA-certified labs can report clinical genetic testing results to patients in the United States

Detailed report insights

A detailed interpretation of your baby’s test results will be provided within 6 to 8 weeks after the delivery of your baby. The report will include recommendations to help you make informed choices about your baby’s condition.

The more you know about your baby, the better equipped you can be to address any potential health problems.

Screening your newborn baby will facilitate early treatment and prevent long term detrimental effects to your baby’s health.

Standard Baby Genetic Screening Comprehensive Baby Genetic Screening

241 types chromosomal abnormalities + 2 conditions:

  • ADHD
  • Atopic Dermatitis

241 types chromosomal abnormalities + 6 conditions:

  • ADHD
  • Atopic Dermatitis (Eczema)
  • Asthma
  • Allergic rhinitis
  • Wilson disease
  • Hearing loss

Frequently Asked Questions

Since the hospital has already conducted tests on my baby, do I still need the Cordlife Baby Genetic Screening?

Cordlife Baby Genetic Screening provides you an expanded coverage of conditions beyond the checks conducted at the hospital. With the access to more information of your baby’s health, you can take preemptive measures to manage the potential conditions that your child is predisposed to. This small step can help to make a difference in your child’s development and overall health.

What should I do if the test result is positive?

Genetic counseling service is available upon request. Our qualified genetic counselor will help you understand the result better and provide holistic advice on the follow-up options that you can take.

Disclaimer and Test Limitation:

Cordlife Baby Genetic Screening is tested by Eone-Diagnomics Genome Centre (EDGC), a CLIA-certified clinical lab based in South Korea with leading-edge technology for genome analysis. EDGC has a quality management system in place to ensure maximum accuracy of screening results. The test is only highly accurate for chromosomal abnormalities of aneuploidies, deletions and duplications (>200kb). As with any screening tests, false positive or false negative results cannot be completely eliminated due to various reasons including but not limited to specimen quality and other variables. This is a genetic screening test related to the genetic predisposition developmental disorders. It cannot be considered as a diagnostic test. Hence, the risk of a disorder should never be precluded solely on the basis of screening. If pathogenic variants are detected, follow up testing is recommended to confirm the results. Signs or symptoms observed should be followed up immediately by a professional healthcare provider.

Reference:

1. Genetic profile and clinical application of chromosomal microarray in children with intellectual disability in Hong Kong. Hong Kong Med J. 2018;24:451-9.

Thứ tư, 10 Tháng 1 2024 09:58

Preimplantation Genetic Screening

Cordlife Preimplantation Genetic Screening (PGS)

Cordlife PGS (Preimplantation Genetic Screening) is the procedure of evaluating embryos for chromosomal aneuploidy, the presence of either addition or loss of chromosomes in embryos generated from chromosomally normal parents. In conjunction with in vitro fertilization (IVF) treatment, Cordlife PGS helps to improve the likelihood of a successful pregnancy while reducing the chance of miscarriage or having a child with gross chromosomal disorders.

“Research has shown that transfer an embryo after PGS has higher rate of a successful pregnancy, from 22% to 41%.1

Who should consider Cordlife PGS?

PGS test is highly beneficial to women above 37 years old. This test helps to improve pregnancy and live birth rate.

Women of advanced
maternal age

Women with recurrent
pregnancy loss

Men with infertility
issues

Women with repeated implantation failure

Carriers of chromosomal
abnormalities

Mothers who had given birth to a child with chromosomal abnormalities

Why Cordlife PGS?

Comprehensive Test

Screens all 23 pairs of chromosomes

Employs Next Generation Sequencing (NGS)

screen for embryo aneuploidy and/or DNA gains or losses (larger than 20Mb)

Highest Quality Assurance

Tested by largest prenatal laboratory in Taiwan with CAP-accreditation and illumina CSPro-certified process

Quick Turnaround

Test result will be available within 3 weeks from the date of sample receipt by the laboratory

99.9%3

Accuracy rate

5 Simple Steps To Enrol Cordlife PGS

Step 1: Consultation

Consult your doctor or fertility specialist

Step 2: Collection

Doctor or fertility specialist will collect samples (Trophectoderm cells / Blastocyst).

Step 3: Sequence

Your samples will be delivered to the sequencing laboratory in Taiwan for analysis.

Step 4: Report

Reports will be available in 3 weeks.

Step 5: Transfer

Based on the PGS test results, your doctor or fertility specialist will select and transfer healthy embryos to the uterus.

Enrolling Cordlife PGS

Cordlife PGS must be prescribed by your obstetrician who will explain the details about PGS to ensure the test is suitable for you. Please enquire with your obstetrician today or send us an email.

Caution

No test is perfect. The results of the PGS test are specific to the samples it tests. The results of these tests are useful as supporting evidence for healthcare providers, and do not represent a final diagnostic conclusion. PGS test results are NOT a diagnostic test. If a chromosomal abnormality (aneuploidy/deletion/duplication) is found, it is the responsibility of the health care provider to provide guidance and recommendations according to current knowledge regarding the disorder. Although the results of these tests are generally conclusive, not all chromosomal abnormalities may be detected, depending on chromosomal or embryonic status or other causes.

Cordlife PGS brought to you by CL BIOTECH COMPANY LIMITED cooperates with a laboratory based in Taiwan - Genetics Generation Advancement Corp. (GGA).

Source:

  1. Liss J, Pastuszek E, Pukszta S et al. Effect of next-generation sequencing in preimplantation genetic testing on live birth ratio. Reprod Fertil Dev. 2018;30(12):1720-1727.
  2. Kang, Hey-Joo et al. Preimplantation genetic screening: who benefits?
    Fertility and Sterility. 2016; 106(3):597 – 602. https://www.fertstert.org/article/S0015-0282(16)61124-X/fulltext . Accessed March 5, 2019.
  3. Fiorentino F, Biricik A, Bono S et al. Development and validation of a next-generation sequencing-based protocol for 24-chromosome aneuploidy screening of embryos. Fertile Sterile. 2014;101(5):1375-82. https://www.ncbi.nlm.nih.gov/pubmed/24613537 . Accessed December 5, 2019.
Thứ hai, 08 Tháng 1 2024 21:31

Lifestyle Genetic Test

Know your health, like the back of your hand

CORDLIFE LIFESTYLE GENETIC TESTS PROVIDE A COMPREHENSIVE PICTURE OF YOUR HEALTH

Each of us has a unique set of inherited genes that gives us a different makeup. With the personalised insights provided by our detailed tests’ reports, you can find out how your gene expressions affect your physiological behaviour, abilities, and more to optimise your overall well-being.

CORDLIFE DIET

Take charge of your diet and weight management.

Covers 18 categories such as diet preferences, weight management, body shape inclination, fat burning ability, nutrients, and food sensitivities.

CORDLIFE HEALTH

Anticipate and prevent potential risk of diseases.

Covers 23 health conditions, including high blood pressure, risk of eczema, nasal allergy, and food allergies.

CORDLIFE SKIN

Attain flawless complexion with personalised skincare regime

Covers 7 common skin issues such as risk of freckle formation, acne formation, and antioxidant capacity.

CORDLIFE SPORTS

Discover your ideal fitness routine to maximise your potential.

Covers 8 major sports characteristics and risks, including muscular endurance, weight/muscle ratio, and post exercise recovery.


Why choose Cordlife lifestyle genetic test?


The collection of your DNA sample is very simple and painless using a cheek swab that will be provided in your collection kit.

Our tests have been validated and confirmed to provide more than 99.9% analytical accuracy, giving you precise and reliable genetic analysis.

Your test results will be analysed, and reports with insights and recommendations tailored for you will be generated, allowing you to take the first steps to making a positive change in your life.

Getting Started

Get your personalised Cordlife lifestyle genetic test reports in 3 easy steps.
Step 1

Sign up today to receive a collection kit with a cheek swab that you can use to collect your test specimen easily and painlessly.

Step 2

Once you have collected your specimen, contact us to arrange for a complimentary pick-up by our professional courier.

Step 3

Relax while we analyse your results. You will receive your comprehensive and personalised reports within 20 working days.

Frequently Asked Questions

What is the science behind Cordlife lifestyle genetic test?

Genes carry genetic information, which is a set of instructions that serve as the body's blueprint. Each individual's characteristics, such as appearance, personality, physique, ability to absorb nutrients, and athletic performance, are influenced not only by genetic factors but also by gene expression. By detecting your own unique gene sequence and locus variation, you can gain a better understanding of your own physical characteristics, allowing you to develop personalised lifestyle habits and health management strategies.

How can I order Cordlife lifestyle genetic test?

Click here to complete your information and receive a collection kit containing a cheek swab that you can use to easily and painlessly collect your test specimen. Once you have collected your specimen, contact us and our professional courier will come over to your place to pick it up.

How soon will I get my results?

Your personalised reports will be made available to you within 20 business days of receiving your test specimen.

Who can take the lifestyle genetic test?

Our lifestyle genetic tests are available to individuals of all ages.

Why should I choose Cordlife?

The testing of your specimen will be performed by our team of scientists with years of experience in laboratory management and the development of bioinformatics for human genetics. We will also compare your results to a large Asian SNP genotyping database to derive a more precise and accurate assessment, as genetic coding patterns vary between populations. By choosing a Cordlife lifestyle genetic test, you are assured of results that are most relevant to your ethnicity.

Disclaimer and Test Limitation

Cordlife’s panel of lifestyle genetic services is distributed by CL Biotech Company Limited and tested by Cordlife (Hong Kong) Limited. The reports are provided solely for informational purposes and should not be construed as medical advice. The reports’ recommendations are not intended to treat, diagnose, or cure any medical conditions or diseases. No laboratory test is completely accurate. Depending on the test you choose, this service is designed to detect variants within a specific reportable range of selected genes that are known to be associated with an increased risk for certain types of inherited disorders, personal traits, nutritional needs, and/or exercise responses, but this test may not detect every variant linked. The findings are derived using current information from the medical literature and scientific databases, as well as laboratory informatics and algorithms that are subjected to changes. For a complete list of disclaimers, please contact Cordlife.

Thứ hai, 08 Tháng 1 2024 17:37

Cordlife NIPT

Cordlife NIPT

Cordlife NIPT gives you an accurate insight into your pregnancy

From a simple blood draw as early as 10 weeks into your pregnancy, Cordlife NIPT screens for the most common chromosomal abnormalities that can affect your developing baby’s future. This test is done with little or no risk to your pregnancy.

  • simple blood test to screen for chromosomal abnormalities of the developing baby. Carries little or no risk to your pregnancy.
  • Can be performed as early as on the 10th week of pregnancy. Twin pregnancy can be tested.
  • Employs Whole Genome Sequencing method for comprehensive coverage of all chromosomes.
  • More than 99% accuracy rate
  • Option to know your baby’s fetal sex
  • Tested by an internationally certified laboratory in South Korea.
  • 3 panels available to detect up to 142 conditions. Option to know your baby’s gender.
  • Up to US$300 confirmatory testing subsidy for patients detected with high-risk of chromosomal abnormalities.

Conventional Prenatal Tests vs Cordlife NIPT

Conventional maternal marker-based prenatal tests such as triple tests, quad tests and integrated tests carry a high false positive rate of 5% or more. This means that of those who were diagnosed as high-risk through these tests, only 2 to 3 percent of them actually have Down syndrome. The rest of the group are perfectly normal but were misdiagnosed as part of the high risk group.

More accurate test reduce need for unnecessary invasive prenatal test

As high risk group patients are usually required to go through risky invasive test such as amniotic fluid test for confirmation, which exposes them to the risk of side effects including miscarriage, choosing a more reliable and accurate test will spare expectant mothers from unnecessary agony and anxiety. The table below compares the various prenatal tests available in the market today.

Cordlife NIPT CONVENTIONAL SERUM TESTS CONFIRMATORY TESTS
Detection Rate (T21) >99% 80% – 95% 99.99%
False Positive Rate (T21) 1.49% 3-5% less than 1%
Possible risk No (non-invasive) No (non-invasive) Yes (invasive)
Specimen 10ml of blood 5ml of blood Amniotic fluid or chorionic cells
Test period As early as 10 weeks 10- 22 weeks 10 – 20 weeks
Test method Next generation sequencing Serum biochemical markers Cultivation using amniotic fluid or chorionic cells
Turnaround time 7-10 working days 4 – 5 weeks 2 – 3 weeks

Source

  1. Practice Bulletin No. 163: Screening for Fetal Aneuploidy; American college of Obstetrics & Gynaecologists. 127(5):e123–e137, May 2016.
  2. Kim MJ, Chang HK, Kim DI, Hee SU, Park S, Kim JH, Bae JS, Lee MH, Lee MS. Validation of fetus aneuploidy in 221 Korean clinical samples using non-invasive chromosome examination; J Genet Med 2015;12(2):79-84, May 2015.
  3. Non-Invasive Prenatal Testing (NIPT) Factsheet; National Coalition for Health Professional education in Genetics, 21 November 2012.

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Pregnancy

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Non-Invasive Prenatal Testing (NIPT)

A screening test using whole genome sequencing to analyse cell-free foetal DNA present in maternal blood as early as 10 weeks of pregnancy to detect the risk of chromosomal abnormalities.

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Preimplantation Genetic Screening

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Newborns & Children

Baby Genetic Screening

A screening for chromosomal abnormalities and gene variants connected to more than 200 genetic disorders in babies using a simple heel prick.

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A non-invasive genetic test that scientifically assesses a child’s certain innate abilities and personality traits to help parents understand their child’s genetic potential.

Adults

Lifestyle Genetic Screening

Learn how you crack the code on your health and gain important insights form your unique genetic blueprint. With Cordlife lifestyle genetic tests, you can take actionable steps to improve your overall lifestyle and begin your journey to better health.